Datuk Amran is currently an Executive Director, Head, Malaysian Investments of Khazanah Nasional Berhad. He began his career in 1997 as a Corporate Finance Executive in Petroliam Nasional Berhad followed by other key positions in several organisations before joining Khazanah Nasional Berhad in 2011. Datuk Amran is a graduate from the McIntire School of Commerce, University of Virginia.
He is currently the Chairman of UEM Group Berhad, sits on the boards of Malaysia Airports Holdings Berhad and Iskandar Investment Berhad, and was formerly on the board of Tenaga Nasional Berhad. Datuk Amran also holds several directorships in a number of private limited companies. Additionally, he is an Adjunct Professor at University Putra Malaysia.